Tuesday, August 6, 2013

Course name: Fundamentals of Biochemistry



Course BT-103                              Full Marks: 100                                                     Unit 1                   Credit 3.5                                                                                                                                                                                

1. Concept of Life:
Definition, Scope and achievement of Biochemistry, Biomolecules; Definition and types of biomolecules, common functional groups of biomolecules.

2. Carbohydrate:
Definition, classification, and properties, chemical reactions, ascending and descending reaction mutarotation, ring structure, invert sugar, reducing sugar, Structure, Properties and functions of disaccharides and polysaccharides; qualitative test for carbohydrates, biological function of carbohydrates.

3. Lipid:
Definition, classification, properties and characterization of lipids, fatty acids: general formula, nomenclature and properties; concept of odd number and even number containing fatty acids and their occurrence; Essential and nonessential fatty acids; difference between fat and oil, rancidity of fats, properties of fats and oils, biological function of lipids.
4. Amino acids:

Definition, structure, classification, physicochemical properties, ionization of amino acid in solution,  isoeletric pH, Titration curve of amino acids, general reaction and color test of amino acids, essential and nonessential amino acids, nonstandard amino acids.  
5. Peptide and Proteins:

Definition of peptide and protein, chemical synthesis of a peptide, classification of proteins, Primary (Peptide bond), Secondary (α helical & β conformation), Tertiary and Quaternary structure of protein, denaturation and renaturation of proteins, color tests and biological functions of protein.
6. Vitamins:

Sources, structure, physiological and biochemical functions, Sources, structure, active form, function and deficiency symptoms of water soluble vitamins (Vit. C and Vit. B complex). Absorption and secretion ot Vitamins.
7. Minerals:

Sources, classification, Biochemical and physiological function and deficiency symptoms of the following minerals- Calcium, Iron, Manganese, Cobalt, Sodium, Potassium, Phosphorus and Chlorine, Absorption and secretion of minerals

Books Recommended:
1.  A. L. Lehinger, David L. Nelson, Michael M. Cox, Principles of Biochemistry (2nd edition).
2. A. C Deb: Fundamental of Biochemistry.
3. Jain: Biochemistry.
4. Lehinger: Text Book of Biochemistry.
5. Styer: Biochemistry.
6. Harper: Biochemistry.


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